2024 Exopolyphosphatase prune1

Exopolyphosphatase prune1

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August undefined, 2024

Webexopolyphosphatase PRUNE1 protein prune homolog prune homolog PubChem 2 Organism-Specific Genes PRUNE1 - prune exopolyphosphatase 1 (human) Prune1 - … WebAug 15, 2016 · The prognosis of patients with colorectal liver metastases (CRLM) remains low despite advances in chemotherapy and surgery. The expression of h-prune (human homolog of Drosophila prune protein; HGNC13420), an exopolyphosphatase, is correlated with progression and aggressiveness in several cancers and promotes migration and …

NMIHBA results from hypomorphic PRUNE1 variants that lack …

WebJul 15, 2024 · prune exopolyphosphatase 1 Location Chromosome 1 (1q21.3) Function PRUNE1 codes for a member of the DHH phosphoesterase family ( Reymond et al., … WebExopolyphosphatase PRUNE1 Definition: Phosphodiesterase (PDE) that has higher activity toward cAMP than cGMP, as substrate. Plays a role in cell proliferation, migration … crb check england

KEGG ORTHOLOGY: K01514

WebThis protein has been found to function as both a nucleotide phosphodiesterase and an exopolyphosphatase. This protein is believed to stimulate cancer progression and metastases through the induction of cell motility. A pseuodgene has been identified on chromosome 13. Alternative splicing results in multiple transcript variants. http://www.informatics.jax.org/marker/MGI:1925152 WebExopolyphosphatase PRUNE1 Gene PRUNE1 Source organism Homo sapiens (Human) go to search UniProt Q86TP1 go to UniProt Experimental structures None available in the PDB Biological function Phosphodiesterase (PDE) that has higher activity toward cAMP than cGMP, as substrate. crb changes

Pharos : Target Details - PRUNE1

WebExopolyphosphatase PRUNE1 (Human) UniProt Q86TP1 - PRUN1_HUMAN. Gene PRUNE1 View Product On Supplier's Website Request a Quote from Cusabio. ... PRUNE1, PRUNE, DRES17, HTCD37, NMIHBA, DRES-17, H-PRUNE. View additional product information. Experiments from the literature. Reactivity. None Available. WebPRUNE1, prune exopolyphosphatase 1 Vertebrate Orthologs 3 Vertebrate Orthology Source. Alliance of Genome Resources. Human Ortholog PRUNE1, prune exopolyphosphatase 1. Synonyms DRES17, DRES-17, … crb check cheapWebGene target information for PRUNE1 - prune exopolyphosphatase 1 (human). Find diseases associated with this biological target and compounds tested against it in … crb check enhanced

"WebPharos : Target Details - PRUNE1 Jump to section: close Descriptive Data Protein Summary Protein Classes IDG Development Level Summary Expression Data Protein Sequence … " - Exopolyphosphatase prune1

Exopolyphosphatase prune1

Web128337365 (PRUNE1) Enzymes [BR:hcg01000] 3. Hydrolases 3.6 Acting on acid anhydrides 3.6.1 In phosphorus-containing anhydrides 3.6.1.11 exopolyphosphatase 128337365 (PRUNE1) BRITE hierarchy: Other DBs: NCBI-GeneID: 128337365: NCBI-ProteinID: XP_053134263: LinkDB: All DBs: Position: 14. AA seq: WebOct 21, 2024 · The PRUNE1 gene encodes a member of the DHH phosphoesterase family, which are enzymes that hydrolyze phosphoester bonds of a broad spectrum of …

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Web(Click on the icon in the table below to see search hit context) WebApr 4, 2024 · The PRUNE1 gene, located on chromosome 1q21.3, encodes a 453 amino acid protein, that is, highly expressed in the human fetal brain and involved in the regulation of neuronal migration and proliferation [ 4 ]. It harbors 2 domains DHH (20–172 amino acids) and DHHA2 (215–359 amino acids).

WebOct 22, 2024 · Thus, the crucial role of polyPs in cell metabolism is clear, as also confirmed in transgenic mice widely expressing the scPPX1 exopolyphosphatase that displayed a reduced mitochondrial respiration in muscles . Prune_1 Protein Interaction With Protein Binding Partners. Human Prune_1 is a naturally unfolded multi-domain adaptor protein. WebThis protein has been found to function as both a nucleotide phosphodiesterase and an exopolyphosphatase. This protein is believed to stimulate cancer progression and metastases through the induction of cell motility.

WebFeb 23, 2024 · PRUNE1 c.933G>A synonymous variant induces exon 7 skipping, disrupts the DHHA2 domain, and leads to an atypical NMIHBA syndrome presentation: Case … WebPrune exopolyphosphatase 1. Gene namei. Official gene symbol, which is typically a short form of the gene name, according to HGNC. PRUNE1 (DRES-17, H-PRUNE, HTCD37, PRUNE) Protein classi. Assigned HPA protein class (es) for the encoded protein (s). Read more. Disease related genes. Enzymes.

WebPrune1 Overexpression Constructs, supplied by OriGene, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ... (left panel). Short-chain exopolyphosphatase activity of wild type, D106N* and R128Q* mutants on P3 and P4 determined using fixed-time BIOMOL Green phosphate detection assay (middle and right …

WebMar 21, 2024 · PRUNE1 prune exopolyphosphatase 1 Gene ID: 58497, updated on 4-Dec-2024 Gene type: protein coding Also known as: PRUNE; DRES17; HTCD37; NMIHBA; … crb check costsWebDec 4, 2024 · PRUNE1 prune exopolyphosphatase 1 [ (human)] Gene ID: 58497, updated on 4-Dec-2024 Summary This gene encodes a member of the DHH protein superfamily … crb check driving instructorWebPRUNE1 is ubiquitously expressed across multiple tissues with widespread central nervous system expression during fetal development in humans ( 5 ). Previous studies have implicated PRUNE1 in a complex network of interactions regulating cell cycle and motility, with elevated PRUNE1 expression associated with cancer metastasis ( 6–8 ). dlss geforceWebJul 1, 2013 · Description. Prune, a 62 kDa protein, belongs to the DHH family phosphoesterase proteins including RecJ DNA repair exonucleases, … dlss games on game passWebJan 6, 2024 · NMIHBA is caused by biallelic variants in PRUNE1 encoding prune exopolyphosphatase 1. We provide in-depth clinical description of two affected siblings harboring compound heterozygous variant alleles, c.383G > A (p.Arg128Gln), c.520G > T (p.Gly174*) in PRUNE1. To gain insights into disease biology, we biochemically … dlss ghosting cyberpunkWebMay 5, 2009 · Exopolyphosphatase PRUNE1 EC number EC:3.6.1.1 ( UniProtKB ENZYME Rhea) Alternative names Drosophila-related expressed sequence 17 ( DRES … dlss games list redditWebMar 3, 2024 · exopolyphosphatase PRUNE1: CCP110: centriolar coiled-coil protein of 110 kDa: SEC16A: protein transport protein Sec16A: CRYBG3: very large A-kinase anchor protein: SPAG5: sperm-associated antigen 5: DCP1A: mRNA-decapping enzyme 1A: STON1: stonin-1: DCP1B: mRNA-decapping enzyme 1B: TRAK1: trafficking kinesin … dlss games support