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Hepatocellularity翻译

Web1 jan. 2007 · Abstract. Reported predictions of human in vivo hepatic clearance from in vitro data have used a variety of values for the scaling factors human microsomal protein (MPPGL) and hepatocellularity (HPGL) per gram of liver, generally with no consideration of the extent of their inter-individual variability. We have collated and analysed data from a ... Web12 sep. 2003 · Bayliss commented recently on hepatocellularity values, emphasizing the uncertainty of interspecies scaling and indicating that appropriate scaling factors remain to be clarified. Therefore, although the value of 120 × 10 6 cells per gram of liver has often been used in human IVIVE [ 18, 19 ], its accuracy in relation to interindividual differences …

Effect of Age on The Hepatocellularity Number for Wistar rats

WebHepatocellularity numbers were calculated from the ratio between the liver protein concentration and the protein concentration in the corresponding hepatocyte suspension. … Web肝细胞癌 (HCC),Hepatocellular Carcinoma (HCC),音标,读音,翻译,英文例句,英语词典 1) Hepatocellular Carcinoma (HCC) 肝细胞癌 (HCC) 2) Hepatocellular carcinoma 肝细胞肝 … good times and tan lines https://matthewdscott.com

VALUES OF HUMAN HEPATOCELLULARITY PER GRAM OF LIVER …

Web34 Current Drug Metabolism, 2007, Vol. 8, No. 1 Barter et al. weight to give an estimate of whole organ intrinsic clear-ance. The scaling factors for data from liver microsomes, hepatocytes ... WebReported predictions of human in vivo hepatic clearance from in vitro data have used a variety of values for the scaling factors human microsomal protein (MPPGL) and hepatocellularity (HPGL) per gram of liver, generally with no consideration of the extent of their inter-individual variability. We have collated and analysed data from a number of … Web28 jul. 2016 · The hepatocellularity of the Göttingen minipig was assessed based on the DNA and the protein quantification methods previously used for other species (53,58). For both methodologies, specific amounts of hepatocytes suspension cultures were compared to a specific amount of homogenized liver tissue, assuming that the liver tissue is mainly … good times and bad times synonyms

Inter‐individual variability in levels of human microsomal ... - Wiley

Category:肝细胞癌(HCC),Hepatocellular Carcinoma (HCC),音标,读音,翻译,英 …

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Hepatocellularity翻译

HEPATOCELLULAR在剑桥英语词典中的解释及翻译

WebMicrosomal protein per gram of liver (MPPGL) and hepatocellularity number per gram of liver (HPGL) using CYP P450 content method ranged 41–73 mg/gram of liver (mean= 57 … WebWilson ZE, Rostami-Hodjegan A, Burn JL, Tooley A, Boyle J, Ellis SW, Tucker GT. Inter-individual variability in levels of human microsomal protein and hepatocellularity per gram of liver. Br J Clin Pharmacol. 2003 Oct56(4):433-40. abstract PubMed ID 12968989: Method

Hepatocellularity翻译

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Webhepatocellularity (3.1×109 cells per kilogram body weight, dotted line in Fig. 1)(27). Similar regression analyses for different datasets found that the empirical scaling factors necessary for accurate predictions were 5.2-fold (35) and 5.6-fold larger (45) than hepatocellularity (2.5–3.1×109 cells per Web1 aug. 1997 · Microsomal protein recovery and hepatocellularity have been determined and investigated as scaling factors for interrelating clearance by hepatic microsomes, freshly isolated hepatocytes and whole liver from untreated (UT) rats and rats treated with either the cytochrome P450 inducer phenobarbital (PB) or dexamethasone (DEX).

WebMean geo hepatocellularity was 163 × 10 6 cells g −1 liver for Wistar rats (95% CI = 127–199 × 10 6 cells g −1 liver) and 169 × 10 6 cells g −1 liver (95% CI = 131–207 × 10 6 cells g −1 liver) for beagle dogs. The data generated in this study indicate a consistency in scaling factors between rat and dog. WebMean(geo) hepatocellularity was 163 x 10(6) cells g(-1) liver for Wistar rats (95% CI = 127-199 x 10(6) cells g(-1) liver) and 169 x 10(6) cells g(-1) liver (95% CI = 131-207 x 10(6) …

WebThe present work profiles the hepatocellularity number in male Wistar rats as a function of age. Using the NADPH–cytochrome P450 reductase (NCR) activity method, the mean HPGL for the adult rat (8 weeks) was 104 × 106 cells/gram liver …

Web1 dec. 2006 · Hepatocellularity numbers were calculated from the ratio between the liver protein concentration and the protein concentration in the corresponding hepatocyte …

Web英 [hepətəʊ'seljʊlə] 美 [hepətoʊ'seljʊlə] 是什么意思 adj. 肝细胞的； 学习怎么用 词组短语 hepatocellular carcinoma 肝细胞癌；肝细胞性肝癌 权威例句 Mutational hot spot in the … chevy 292 inline 6 crate engine upgragesWeb1 dec. 2006 · Biotransformation rates measured using cryopreserved trout hepatocytes can be extrapolated to the whole animal to predict metabolism impacts on chemical bioaccumulation, and hepatocytes from male and female juvenile trout may be used interchangeably for in vitro–in vivo metabolism extrapolations. Expand 25 Highly Influenced chevy 292 head gasket setWebhepatocellular 音标：/ˌhepətəu'seljulə/ 全球发音： 生词本： 添加笔记： 有奖纠错 划词 英汉-汉英词典 词组搭配 英语例句库 全文检索 英汉-汉英词典 adj. 细胞的 词组 习惯用语 … chevy 292 inline 6 turbo manifoldWebReported predictions of human in vivo hepatic clearance from in vitro data have used a variety of values for the scaling factors human microsomal protein (MPPGL) and … chevy 292 vs ford 300Web1 feb. 2014 · Determination of the hepatocellularity number for human, dog, rabbit, rat and mouse livers from protein concentration measurements. Toxicol In Vitro (2006) L.T. Lee et al. Removal of unbound sodium dodecyl sulfate (SDS) from proteins in solution by electrophoresis through triton X-100-agarose. chevy 292 split exhaust headerWeb1. Scaling factor values for the in vitro-in vivo extrapolation of hepatic metabolic clearance for xenobiotics have not yet been determined in horses. Scaling factors were determined … chevy 292 hei distributorWebAging hepatocellularity horse liver microsomal scaling factors Supplementary material available online chevy 292 rebuild kit